Yes. The government charges a US $50 penalty if you don't pay your annual business franchise tax on time. After the first penalty, the government charges a second penalty of US$300 for non-payment of two consecutive tax periods. Our law firm charges a $50 penalty per tax period, for non-payment of resident agent/registered office/CEO fees. It is very important to keep your entity in good standing, otherwise the Panama Public Registry will delete the company registration and therefore it would be costly to reactivate it.